Maximize the potential of your Antibodies with our Optimization services

Naturally occurring or in vitro-generated antibodies often do not have the ideal properties for therapeutic, diagnostic, or industrial applications. As a leading antibody CRO, we offer a range of services to help tailor your antibodies for improved efficacy, safety, manufacturability, and regulatory compliance.

Partner with us for precision-driven results!

Affinity Maturation

At LxBio AB, we have extensive experience in affinity maturation library construction. By applying random mutagenesis, primarily in the CDR regions, to generate sub-libraries of parental antibody variants, we create higher-affinity candidates.

Vector construction and cloning
Expression in host cells (e.g., CHO)
Purification and quality assessment

Antibody Conversion

We provide humanization of murine or other species-derived antibodies, reducing immunogenicity and improving safety for human use. If you require different antibody formats, we offer engineering services to convert your antibody to the desired format and ensure that the format change does not compromise binding affinity, specificity, or functionality.

Effector Function Optimization

Effector functions are critical to the therapeutic efficacy of antibodies. By engineering the Fc region and understanding the interplay between antigen binding and immune system activation, we enhance your antibody’s ability to deliver maximum therapeutic benefit.

Contact us today to discuss our Antibody Optimization services.

We can help you accelerate the development of your therapeutic antibody candidates.
We’re here to help you achieve the desired TPP.